Complement 3 Deficiency
Most affected breeds
- Brittany Spaniel
Ameratunga R, Winkelstein JA, Brody L,et al. Molecular analysis of the third component of canine complement (C3) and identification of the mutation responsible for hereditary canine C3 deficiency. J Immunol. 1998 Mar 15;160(6):2824-30.
Winkelstein JA, Cork LC, Griffin DE,et al. Genetically determined deficiency of the third component of complement in the dog. Science. 1981 Jun 5;212(4499):1169-70.